*Product availability is subject to suppliers inventory
About the Book
"The science of molecular genetics began with the determination of the structure of DNA. Experiments with bacteria and phages (i.e., viruses that infect bacteria) in the late 1940s and early 1950s, as well as the presence of DNA in chromosomes of higher organisms, had implicated this macromolecule as the hereditary material (see the introduction). In the 1930s, biochemical studies of the base composition of DNA by Erwin Chargaff established that the amount of guanine always equals the amount of cytosine and that the amount of adenine always equals the amount of thymine, independent of the total base composition of the DNA. In the early 1950s, X-ray diffraction studies by Rosalind Franklin and Maurice Wilkins showed that DNA is a double helix. Finally, in 1953, Francis Crick and James Watson put together the chemical and X-ray diffraction information in their famous model of the structure of DNA. This story is one of the most dramatic in the history of science and has been the subject of many historical treatments, some of which are listed at the end of this chapter"--Book Synopsis
The single most comprehensive and authoritative textbook on bacterial molecular genetics
Snyder & Champness Molecular Genetics of Bacteria is a new edition of a classic text, updated to address the massive advances in the field of bacterial molecular genetics and retitled as homage to the founding authors.
In an era experiencing an avalanche of new genetic sequence information, this updated edition presents important experiments and advanced material relevant to current applications of molecular genetics, including conclusions from and applications of genomics; the relationships among recombination, replication, and repair and the importance of organizing sequences in DNA; the mechanisms of regulation of gene expression; the newest advances in bacterial cell biology; and the coordination of cellular processes during the bacterial cell cycle. The topics are integrated throughout with biochemical, genomic, and structural information, allowing readers to gain a deeper understanding of modern bacterial molecular genetics and its relationship to other fields of modern biology.
Although the text is centered on the most-studied bacteria, Escherichia coli and Bacillus subtilis, many examples are drawn from other bacteria of experimental, medical, ecological, and biotechnological importance. The book's many useful features include
While intended as an undergraduate or beginning graduate textbook, Molecular Genetics of Bacteria is an invaluable reference for anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology.
This is a marvelous textbook that is completely up-to-date and comprehensive, but not overwhelming. The clear prose and excellent figures make it ideal for use in teaching bacterial molecular genetics.
--Caroline Harwood, University of Washington
About the Author
Tina M. Henkin is Professor of Microbiology and Robert W. and Estelle S. Bingham Professor of Biological Sciences at Ohio State University, where she has been teaching since 1995. Dr. Henkin received a PhD in genetics at the University of Wisconsin.
Joseph E. Peters is Professor of Microbiology and Director of the Graduate Program in Microbiology at Cornell University, where he has been teaching since 2002. Dr. Peters received a PhD in microbiology at the University of Maryland.